Pseudomonas aeruginosa PAO1, PA0938 (wzz2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0938
Name
wzz2
Replicon chromosome
Genomic location 1028172 - 1029500 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249629.1
GI 15596135
Affymetrix PA0938_at
Entrez 880291
GenBank AAG04327.1
INSDC AAG04327.1
NCBI Locus Tag PA0938
protein_id(GenBank) gb|AAG04327.1|AE004528_5|gnl|PseudoCAP|PA0938
TIGR NTL03PA00939
UniParc UPI00000C51CA
UniProtKB Acc Q9I520
UniProtKB ID Q9I520_PSEAE
UniRef100 UniRef100_Q9I520
UniRef50 UniRef50_Q9I520
UniRef90 UniRef90_Q9I520

Product

Feature Type CDS
Coding Frame 1
Product Name
Wzz2
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (49.27 kDa, PMID:21751344)
Charge (pH 7) 4.26
Kyte-Doolittle Hydrophobicity Value -0.276
Molecular Weight (kDa) 49.3
Isoelectric Point (pI) 9.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000904 (725 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0938
Search term: wzz2
Search term: Wzz2

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas aeruginosa B-band O-antigen chain length is modulated by Wzz (Ro1).
Burrows LL, Chow D, Lam JS
J. Bacteriol. 1997 Mar;179(5):1482-9
PubMed ID: 9045803
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
Pseudomonas aeruginosa O-antigen chain length is determined before ligation to lipid A core.
Daniels C, Griffiths C, Cowles B, Lam JS
Environ. Microbiol. 2002 Dec;4(12):883-97
PubMed ID: 12534470