Pseudomonas aeruginosa PAO1, PA1188

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1188
Name
Replicon chromosome
Genomic location 1289965 - 1291146 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249879.1
GI 15596385
Affymetrix PA1188_at
DNASU PaCD00006547
Entrez 880017
GenBank AAG04577.1
INSDC AAG04577.1
NCBI Locus Tag PA1188
protein_id(GenBank) gb|AAG04577.1|AE004549_4|gnl|PseudoCAP|PA1188
TIGR NTL03PA01189
UniParc UPI00000C5298
UniProtKB Acc Q9I4F0
UniProtKB ID Q9I4F0_PSEAE
UniRef100 UniRef100_W0YQA2
UniRef50 UniRef50_A0LIG3
UniRef90 UniRef90_B7UX00

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -4.43
Kyte-Doolittle Hydrophobicity Value -0.001
Molecular Weight (kDa) 42.1
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 312 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001146 (416 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1188

Human Homologs

Ensembl 110, assembly GRCh38.p14
succinyl-CoA:glutarate-CoA transferase [Source:HGNC Symbol;Acc:HGNC:16001]
E-value: 1.5e-43
Percent Identity: 29.9

References

Purification and properties of an alpha-methylacyl-CoA racemase from rat liver.
Schmitz W, Fingerhut R, Conzelmann E
Eur J Biochem 1994 Jun 1;222(2):313-23
PubMed ID: 8020470
Molecular cloning of cDNA species for rat and mouse liver alpha-methylacyl-CoA racemases.
Schmitz W, Helander HM, Hiltunen JK, Conzelmann E
Biochem J 1997 Sep 15;326 ( Pt 3)(Pt 3):883-9
PubMed ID: 9307041