Pseudomonas aeruginosa PAO1, PA1275 (cobD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1275
Name
cobD
Synonym: cbiB
Replicon chromosome
Genomic location 1386323 - 1387261 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249966.1
GI 15596472
Affymetrix PA1275_cobD_at
Entrez 881384
GenBank AAG04664.1
INSDC AAG04664.1
NCBI Locus Tag PA1275
protein_id(GenBank) gb|AAG04664.1|AE004557_5|gnl|PseudoCAP|PA1275
TIGR NTL03PA01276
UniParc UPI00000C52E3
UniProtKB Acc Q9I469
UniProtKB ID COBD_PSEAE
UniRef100 UniRef100_Q9I469
UniRef50 UniRef50_Q9I469
UniRef90 UniRef90_Q9I469

Product

Feature Type CDS
Coding Frame 1
Product Name
cobalamin biosynthetic protein CobD
Product Name Confidence: Class 2
Synonyms cobalamin biosynthetic protein CbiB
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.41
Kyte-Doolittle Hydrophobicity Value 0.235
Molecular Weight (kDa) 33.9
Isoelectric Point (pI) 8.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001222 (548 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1275
Search term: cobD

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295