Pseudomonas aeruginosa PAO1, PA1282

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1282
Name
Replicon chromosome
Genomic location 1392564 - 1394069 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq NP_249973.1
GI 15596479
Affymetrix PA1282_at
Entrez 881440
GenBank AAG04671.1
INSDC AAG04671.1
NCBI Locus Tag PA1282
protein_id(GenBank) gb|AAG04671.1|AE004557_12|gnl|PseudoCAP|PA1282
TIGR NTL03PA01283
UniParc UPI00000C52EA
UniProtKB Acc Q9I462
UniProtKB ID Q9I462_PSEAE
UniRef100 UniRef100_Q9I462
UniRef50 UniRef50_Q6CYP9
UniRef90 UniRef90_Q9I462

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 7.08
Kyte-Doolittle Hydrophobicity Value 0.840
Molecular Weight (kDa) 52.6
Isoelectric Point (pI) 9.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 503 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001213 (1391 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1282

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Organisation and functions of the actVA region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor.
Caballero JL, Martinez E, Malpartida F, Hopwood DA
Mol Gen Genet 1991 Dec;230(3):401-12
PubMed ID: 1766437
Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis.
Takiff HE, Cimino M, Musso MC, Weisbrod T, Martinez R, Delgado MB, Salazar L, Bloom BR, Jacobs WR Jr
Proc Natl Acad Sci U S A 1996 Jan 9;93(1):362-6
PubMed ID: 8552639
Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity.
Paulsen IT, Brown MH, Littlejohn TG, Mitchell BA, Skurray RA
Proc Natl Acad Sci U S A 1996 Apr 16;93(8):3630-5
PubMed ID: 8622987