Pseudomonas aeruginosa PAO1, PA1318 (cyoB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1318
Name
cyoB
Replicon chromosome
Genomic location 1429082 - 1431058 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_250009.1
GI 15596515
Affymetrix PA1318_cyoB_at
Entrez 881481
GenBank AAG04707.1
INSDC AAG04707.1
NCBI Locus Tag PA1318
protein_id(GenBank) gb|AAG04707.1|AE004561_3|gnl|PseudoCAP|PA1318
TIGR NTL03PA01319
UniParc UPI00000C530D
UniProtKB Acc Q9I426
UniProtKB ID CYOB_PSEAE
UniRef100 UniRef100_Q9I426
UniRef50 UniRef50_E0TW66
UniRef90 UniRef90_Q9I426

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome o ubiquinol oxidase subunit I
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.71
Kyte-Doolittle Hydrophobicity Value 0.602
Molecular Weight (kDa) 73.9
Isoelectric Point (pI) 9.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 419 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000104 (999 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1318
Search term: cyoB

Human Homologs

Ensembl 110, assembly GRCh38.p14
mitochondrially encoded cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:7419]
E-value: 8.8e-105
Percent Identity: 39.4

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Recent studies of the cytochrome o terminal oxidase complex of Escherichia coli.
Chepuri V, Lemieux L, Hill J, Alben JO, Gennis RB
Biochim Biophys Acta 1990 Jul 25;1018(2-3):124-7
PubMed ID: 2168206