Pseudomonas aeruginosa PAO1, PA1441

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1441
Name
Replicon chromosome
Genomic location 1570496 - 1571779 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250132.1
GI 15596638
Affymetrix PA1441_at
Entrez 881825
GenBank AAG04830.1
INSDC AAG04830.1
NCBI Locus Tag PA1441
protein_id(GenBank) gb|AAG04830.1|AE004574_1|gnl|PseudoCAP|PA1441
TIGR NTL03PA01442
UniParc UPI00000C5383
UniProtKB Acc Q9I3Q6
UniProtKB ID Q9I3Q6_PSEAE
UniRef100 UniRef100_Q9I3Q6
UniRef50 UniRef50_A0A022NYE2
UniRef90 UniRef90_A0A022NYE2

Product

Feature Type CDS
Coding Frame 1
Product Name
putative flagellar hook-length control protein FliK
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -13.49
Kyte-Doolittle Hydrophobicity Value -0.529
Molecular Weight (kDa) 44.2
Isoelectric Point (pI) 4.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 98 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001358 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1441

Human Homologs

References

Flagellar switch of Salmonella typhimurium: gene sequences and deduced protein sequences.
Kihara M, Homma M, Kutsukake K, Macnab RM
J Bacteriol 1989 Jun;171(6):3247-57
PubMed ID: 2656645
Characterization of a Type III secretion substrate specificity switch (T3S4) domain in YscP from Yersinia enterocolitica.
Agrain C, Callebaut I, Journet L, Sorg I, Paroz C, Mota LJ, Cornelis GR
Mol Microbiol 2005 Apr;56(1):54-67
PubMed ID: 15773978
Cloning, purification, crystallization and preliminary X-ray studies of flagellar hook scaffolding protein FlgD from Pseudomonas aeruginosa PAO1.
Luo M, Niu S, Yin Y, Huang A, Wang D
Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 Aug 1;65(Pt 8):795-7
PubMed ID: 19652342