Pseudomonas aeruginosa PAO1, PA1947 (rbsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1947
Name
rbsA
Replicon chromosome
Genomic location 2131835 - 2133367 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250637.1
GI 15597143
Affymetrix PA1947_rbsA_at
Entrez 880680
GenBank AAG05335.1
INSDC AAG05335.1
NCBI Locus Tag PA1947
protein_id(GenBank) gb|AAG05335.1|AE004621_6|gnl|PseudoCAP|PA1947
TIGR NTL03PA01947
UniParc UPI00000C5523
UniProtKB Acc Q9I2F7
UniProtKB ID Q9I2F7_PSEAE
UniRef100 UniRef100_Q9I2F7
UniRef50 UniRef50_N0A514
UniRef90 UniRef90_V6AGZ0

Product

Feature Type CDS
Coding Frame 1
Product Name
ribose transport protein RbsA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.91
Kyte-Doolittle Hydrophobicity Value -0.037
Molecular Weight (kDa) 55.8
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000134 (908 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1947
Search term: rbsA

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:13886]
E-value: 7.5e-11
Percent Identity: 29.2

References

Molecular cloning and characterization of genes required for ribose transport and utilization in Escherichia coli K-12.
Iida A, Harayama S, Iino T, Hazelbauer GL
J Bacteriol 1984 May;158(2):674-82
PubMed ID: 6327617
An analysis of the structure of the product of the rbsA gene of Escherichia coli K12.
Buckel SD, Bell AW, Rao JK, Hermodson MA
J Biol Chem 1986 Jun 15;261(17):7659-62
PubMed ID: 3086314
The proteins encoded by the rbs operon of Escherichia coli: I. Overproduction, purification, characterization, and functional analysis of RbsA.
Barroga CF, Zhang H, Wajih N, Bouyer JH, Hermodson MA
Protein Sci 1996 Jun;5(6):1093-9
PubMed ID: 8762140
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Presecan E, Moszer I, Boursier L, Ramos HC, de la Fuente V, Hullo MF, Lelong C, Schleich S, Sekowska A, Song BH, Villani G, Kunst F, Danchin A, Glaser P
Microbiology (Reading) 1997 Oct;143 ( Pt 10):3313-3328
PubMed ID: 9353933