Pseudomonas aeruginosa PAO1, PA3134 (gltX)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA3134
|
| Name |
gltX
|
| Replicon | chromosome |
| Genomic location | 3515416 - 3516900 (- strand) |
Cross-References
| RefSeq | NP_251824.1 |
| GI | 15598330 |
| Affymetrix | PA3134_gltX_at |
| Entrez | 882647 |
| GenBank | AAG06522.1 |
| INSDC | AAG06522.1 |
| NCBI Locus Tag | PA3134 |
| protein_id(GenBank) | gb|AAG06522.1|AE004737_8|gnl|PseudoCAP|PA3134 |
| TIGR | NTL03PA03134 |
| UniParc | UPI00001363EE |
| UniProtKB Acc | Q9XCL6 |
| UniProtKB ID | SYE_PSEAE |
| UniRef100 | UniRef100_Q9XCL6 |
| UniRef50 | UniRef50_Q9XCL6 |
| UniRef90 | UniRef90_Q9XCL6 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
glutamyl-tRNA synthetase
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -2.58 |
| Kyte-Doolittle Hydrophobicity Value | -0.405 |
| Molecular Weight (kDa) | 56.7 |
| Isoelectric Point (pI) | 6.68 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5TGT | LIGASE | 09/28/16 | Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.45 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002464 (552 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA3134
Search term: gltX
Search term: glutamyl-tRNA synthetase
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
glutamyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29419]
E-value:
3.4e-74
Percent Identity:
35.3
|
References
|
Cloning and sequencing of the gltX gene, encoding the glutamyl-tRNA synthetase of Rhizobium meliloti A2.
Laberge S, Gagnon Y, Bordeleau LM, Lapointe J
J Bacteriol 1989 Jul;171(7):3926-32
PubMed ID: 2661539
|