Pseudomonas aeruginosa PAO1, PA3137

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3137
Name
Replicon chromosome
Genomic location 3519045 - 3520544 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251827.1
GI 15598333
Affymetrix PA3137_at
Entrez 882603
GenBank AAG06525.1
INSDC AAG06525.1
NCBI Locus Tag PA3137
protein_id(GenBank) gb|AAG06525.1|AE004737_11|gnl|PseudoCAP|PA3137
TIGR NTL03PA03137
UniParc UPI00000C5925
UniProtKB Acc Q9HZ88
UniProtKB ID Q9HZ88_PSEAE
UniRef100 UniRef100_A0A0C7CRU1
UniRef50 UniRef50_A0A0A5I847
UniRef90 UniRef90_A6V2T6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 0.58
Kyte-Doolittle Hydrophobicity Value 0.698
Molecular Weight (kDa) 53.7
Isoelectric Point (pI) 7.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002463 (937 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3137

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Emr, an Escherichia coli locus for multidrug resistance.
Lomovskaya O, Lewis K
Proc Natl Acad Sci U S A 1992 Oct 1;89(19):8938-42
PubMed ID: 1409590