Pseudomonas aeruginosa PAO1, PA3145 (wbpL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3145
Name
wbpL
Replicon chromosome
Genomic location 3528428 - 3529447 (- strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251835.1
GI 15598341
Affymetrix PA3145_wbpL_at
Entrez 882697
GenBank AAG06533.1
INSDC AAG06533.1
NCBI Locus Tag PA3145
protein_id(GenBank) gb|AAG06533.1|AE004738_7|gnl|PseudoCAP|PA3145
TIGR NTL03PA03145
UniParc UPI00000DA10A
UniProtKB Acc G3XD50
UniProtKB ID G3XD50_PSEAE
UniRef100 UniRef100_G3XD50
UniRef50 UniRef50_G3XD50
UniRef90 UniRef90_G3XD50

Product

Feature Type CDS
Coding Frame 1
Product Name
glycosyltransferase WbpL
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 7.23
Kyte-Doolittle Hydrophobicity Value 0.964
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 8.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002458 (480 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3145
Search term: wbpL

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of rfbA, involved in B-band lipopolysaccharide biosynthesis in Pseudomonas aeruginosa serotype O5.
Dasgupta T, Lam JS
Infect. Immun. 1995 May;63(5):1674-80
PubMed ID: 7537247
Three rhamnosyltransferases responsible for assembly of the A-band D-rhamnan polysaccharide in Pseudomonas aeruginosa: a fourth transferase, WbpL, is required for the initiation of both A-band and B-band lipopolysaccharide synthesis.
Rocchetta HL, Burrows LL, Pacan JC, Lam JS
Mol. Microbiol. 1998 Jun;28(6):1103-19
PubMed ID: 9680202