Pseudomonas aeruginosa PAO1, PA3151 (hisF2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3151
Name
hisF2
Replicon chromosome
Genomic location 3535216 - 3535971 (- strand)

Cross-References

RefSeq NP_251841.1
GI 15598347
Affymetrix PA3151_hisF2_at
DNASU PaCD00007385
Entrez 882582
GenBank AAG06539.1
INSDC AAG06539.1
NCBI Locus Tag PA3151
protein_id(GenBank) gb|AAG06539.1|AE004739_1|gnl|PseudoCAP|PA3151
TIGR NTL03PA03151
UniParc UPI0000001568
UniProtKB Acc P72139
UniProtKB ID HIS62_PSEAE
UniRef100 UniRef100_P72139
UniRef50 UniRef50_P72139
UniRef90 UniRef90_P72139

Product

Feature Type CDS
Coding Frame 1
Product Name
imidazoleglycerol-phosphate synthase, cyclase subunit
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.98
Kyte-Doolittle Hydrophobicity Value 0.082
Molecular Weight (kDa) 27.4
Isoelectric Point (pI) 5.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005136 (53 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3151
Search term: hisF2

Human Homologs

References

Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.
Klem TJ, Davisson VJ
Biochemistry 1993 May;32(19):5177-86
PubMed ID: 8494895