Pseudomonas aeruginosa PAO1, PA3157

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3157
Name
Synonym: wbpC
Replicon chromosome
Genomic location 3540782 - 3542671 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251847.1
GI 15598353
Affymetrix PA3157_at
Entrez 882641
GenBank AAG06545.1
INSDC AAG06545.1
NCBI Locus Tag PA3157
protein_id(GenBank) gb|AAG06545.1|AE004739_7|gnl|PseudoCAP|PA3157
TIGR NTL03PA03157
UniParc UPI00000C592F
UniProtKB Acc Q9HZ74
UniProtKB ID Q9HZ74_PSEAE
UniRef100 UniRef100_Q9HZ74
UniRef50 UniRef50_P72134
UniRef90 UniRef90_P72134

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acetyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 14.85
Kyte-Doolittle Hydrophobicity Value 0.490
Molecular Weight (kDa) 70.0
Isoelectric Point (pI) 9.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 282 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005004 (408 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3157

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: oafA is a member of a family of integral membrane trans-acylases.
Slauch JM, Lee AA, Mahan MJ, Mekalanos JJ
J Bacteriol 1996 Oct;178(20):5904-9
PubMed ID: 8830685
Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
Burrows LL, Charter DF, Lam JS
Mol Microbiol 1996 Nov;22(3):481-95
PubMed ID: 8939432