Pseudomonas aeruginosa PAO1, PA3560 (fruA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3560
Name
fruA
Replicon chromosome
Genomic location 3988838 - 3990595 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252250.1
GI 15598756
Affymetrix PA3560_fruA_at
Entrez 879828
GenBank AAG06948.1
INSDC AAG06948.1
NCBI Locus Tag PA3560
protein_id(GenBank) gb|AAG06948.1|AE004777_1|gnl|PseudoCAP|PA3560
TIGR NTL03PA03560
UniParc UPI00000C5A6A
UniProtKB Acc Q9HY57
UniProtKB ID Q9HY57_PSEAE
UniRef100 UniRef100_Q9HY57
UniRef50 UniRef50_A0KKR8
UniRef90 UniRef90_Q9HY57

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphotransferase system transporter fructose-specific IIBC component, FruA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.23
Kyte-Doolittle Hydrophobicity Value 0.666
Molecular Weight (kDa) 59.0
Isoelectric Point (pI) 8.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002106 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3560
Search term: fruA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence of fruA, the gene specifying enzyme IIfru of the phosphoenolpyruvate-dependent sugar phosphotransferase system in Escherichia coli K12.
Prior TI, Kornberg HL
J Gen Microbiol 1988 Oct;134(10):2757-68
PubMed ID: 3076173