Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4710
|
Name |
phuR
|
Replicon | chromosome |
Genomic location | 5289217 - 5291511 (+ strand) |
Transposon Mutants | 8 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 13 transposon mutants in orthologs |
RefSeq | NP_253398.1 |
GI | 15599904 |
Affymetrix | PA4710_at |
Entrez | 881550 |
GenBank | AAG08096.1 |
INSDC | AAG08096.1 |
NCBI Locus Tag | PA4710 |
protein_id(GenBank) | gb|AAG08096.1|AE004885_1|gnl|PseudoCAP|PA4710 |
TIGR | NTL03PA04711 |
UniParc | UPI00000C5DD8 |
UniProtKB Acc | Q9HV88 |
UniProtKB ID | Q9HV88_PSEAE |
UniRef100 | UniRef100_W0Z1I5 |
UniRef50 | UniRef50_Q4K7S2 |
UniRef90 | UniRef90_B7V1C2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Heme/Hemoglobin uptake outer membrane receptor PhuR precursor
|
Synonyms |
Haem/Haemoglobin uptake outer membrane receptor PhuR precursor |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Verified using two-dimensional gel electrophoresis, MALDI-TOF MS and peptide mass mapping(pI:5.7, molecular weight:84.7, PMID:21674802)
|
Charge (pH 7) | -8.64 |
Kyte-Doolittle Hydrophobicity Value | -0.582 |
Molecular Weight (kDa) | 84.7 |
Isoelectric Point (pI) | 5.94 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 340 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000897 (3061 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4710
Search term: phuR
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Hemin uptake system of Yersinia enterocolitica: similarities with other TonB-dependent systems in gram-negative bacteria.
Stojiljkovic I, Hantke K
EMBO J 1992 Dec;11(12):4359-67
PubMed ID: 1425573
|
Characterization of the Vibrio cholerae outer membrane heme transport protein HutA: sequence of the gene, regulation of expression, and homology to the family of TonB-dependent proteins.
Henderson DP, Payne SM
J Bacteriol 1994 Jun;176(11):3269-77
PubMed ID: 8195082
|
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa.
Hare NJ, Scott NE, Shin EH, Connolly AM, Larsen MR, Palmisano G, Cordwell SJ
Proteomics 2011 Aug;11(15):3056-69
PubMed ID: 21674802
|
Differential contributions of the outer membrane receptors PhuR and HasR to heme acquisition in Pseudomonas aeruginosa.
Smith AD, Wilks A
J Biol Chem 2015 Mar 20;290(12):7756-66
PubMed ID: 25616666
|