Pseudomonas aeruginosa PAO1, PA5415 (glyA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA5415
Name
glyA1
Replicon chromosome
Genomic location 6094024 - 6095277 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254102.1
GI 15600608
Affymetrix PA5415_glyA1_s_at
Entrez 880066
GenBank AAG08800.1
INSDC AAG08800.1
NCBI Locus Tag PA5415
protein_id(GenBank) gb|AAG08800.1|AE004954_2|gnl|PseudoCAP|PA5415
TIGR NTL03PA05416
UniParc UPI000012B4E1
UniProtKB Acc Q9HTE9
UniProtKB ID GLYA1_PSEAE
UniRef100 UniRef100_Q9HTE9
UniRef50 UniRef50_D3DKC4
UniRef90 UniRef90_Q9I138

Product

Feature Type CDS
Coding Frame 1
Product Name
serine hydroxymethyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.99
Kyte-Doolittle Hydrophobicity Value -0.119
Molecular Weight (kDa) 44.7
Isoelectric Point (pI) 6.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 654 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003094 (1189 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5415
Search term: glyA1

Human Homologs

Ensembl 97, assembly GRCh38.p12
serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852]
E-value: 1.7e-94
Percent Identity: 46.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852]
E-value: 1.7e-94
Percent Identity: 46.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852]
E-value: 1.7e-94
Percent Identity: 46.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852]
E-value: 1.7e-94
Percent Identity: 46.0

References

Isolation and nucleotide sequence of the hmp gene that encodes a haemoglobin-like protein in Escherichia coli K-12.
Vasudevan SG, Armarego WL, Shaw DC, Lilley PE, Dixon NE, Poole RK
Mol Gen Genet 1991 Apr;226(1-2):49-58
PubMed ID: 2034230