Pseudomonas aeruginosa PAO1, PA5439

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5439
Name
Replicon chromosome
Genomic location 6122139 - 6123605 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254126.1
GI 15600632
Affymetrix PA5439_at
Entrez 878525
GenBank AAG08824.1
INSDC AAG08824.1
NCBI Locus Tag PA5439
protein_id(GenBank) gb|AAG08824.1|AE004956_8|gnl|PseudoCAP|PA5439
TIGR NTL03PA05440
UniParc UPI00000C6008
UniProtKB Acc Q9HTC7
UniProtKB ID Q9HTC7_PSEAE
UniRef100 UniRef100_Q9HTC7
UniRef50 UniRef50_I7DPV7
UniRef90 UniRef90_A6VEQ4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable glucose-6-phosphate dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.82
Kyte-Doolittle Hydrophobicity Value -0.236
Molecular Weight (kDa) 54.6
Isoelectric Point (pI) 7.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 391 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004990 (399 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5439

Human Homologs

Ensembl 110, assembly GRCh38.p14
glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057]
E-value: 3.6e-79
Percent Identity: 37.8

References

No references are associated with this feature.