Pseudomonas aeruginosa PAO1, PA0005 (lptA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0005
|
| Name |
lptA
Synonym: plsC |
| Replicon | chromosome |
| Genomic location | 7018 - 7791 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
Cross-References
| RefSeq | NP_064725.1 |
| GI | 15595203 |
| Affymetrix | PA0005_at |
| Entrez | 877576 |
| GenBank | AAG03395.1 |
| INSDC | AAG03395.1 |
| NCBI Locus Tag | PA0005 |
| protein_id(GenBank) | gb|AAG03395.1|AE004440_5|gnl|PseudoCAP|PA0005 |
| TIGR | NTL03PA00006 |
| UniParc | UPI00000C4EE2 |
| UniProtKB Acc | Q9I7C1 |
| UniProtKB ID | Q9I7C1_PSEAE |
| UniRef100 | UniRef100_Q9I7C1 |
| UniRef50 | UniRef50_Q9I7C1 |
| UniRef90 | UniRef90_Q9I7C1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
lysophosphatidic acid acyltransferase, LptA
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | 10.86 |
| Kyte-Doolittle Hydrophobicity Value | 0.182 |
| Molecular Weight (kDa) | 28.7 |
| Isoelectric Point (pI) | 10.23 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 465 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000005 (555 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0005
Search term: lptA
Search term: lysophosphatidic acid acyltransferase, LptA
|
Human Homologs
References
|
Modulation of quorum sensing in Pseudomonas aeruginosa through alteration of membrane properties.
Baysse C, Cullinane M, Dénervaud V, Burrowes E, Dow JM, Morrissey JP, Tam L, Trevors JT, O'Gara F
Microbiology 2005 Aug;151(Pt 8):2529-2542
PubMed ID: 16079332
|
|
cDNA cloning and expression of murine 1-acyl-sn-glycerol-3-phosphate acyltransferase.
Kume K, Shimizu T
Biochem. Biophys. Res. Commun. 1997 Aug;237(3):663-6
PubMed ID: 9299423
|