Pseudomonas aeruginosa PAO1, PA0017

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0017
Name
Synonym: fmu
Synonym: sun
Replicon chromosome
Genomic location 18767 - 20071 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248707.1
GI 15595215
Affymetrix PA0017_at
DNASU PaCD00006010
Entrez 879297
GenBank AAG03407.1
INSDC AAG03407.1
NCBI Locus Tag PA0017
protein_id(GenBank) gb|AAG03407.1|AE004441_8|gnl|PseudoCAP|PA0017
TIGR NTL03PA00018
UniParc UPI00000C4EEC
UniProtKB Acc Q9I7A9
UniProtKB ID RSMB_PSEAE
UniRef100 UniRef100_Q9I7A9
UniRef50 UniRef50_Q9I7A9
UniRef90 UniRef90_Q9I7A9

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.15
Kyte-Doolittle Hydrophobicity Value -0.185
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 8.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 581 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000017 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0017

Human Homologs

Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0
Ensembl 107, assembly GRCh38.p13
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 4.7e-27
Percent Identity: 29.0

References

NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.
Schlösser A, Hamann A, Bossemeyer D, Schneider E, Bakker EP
Mol. Microbiol. 1993 Aug;9(3):533-43
PubMed ID: 8412700
Cloning of the trkAH gene cluster and characterization of the Trk K(+)-uptake system of Vibrio alginolyticus.
Nakamura T, Yamamuro N, Stumpe S, Unemoto T, Bakker EP
Microbiology (Reading, Engl.) 1998 Aug;144 ( Pt 8)
PubMed ID: 9720051