Pseudomonas aeruginosa PAO1, PA0025 (aroE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0025
Name
aroE
Replicon chromosome
Genomic location 26711 - 27535 (+ strand)

Cross-References

RefSeq NP_248715.1
GI 15595223
Affymetrix PA0025_aroE_at
DNASU PaCD00006014
Entrez 880894
GenBank AAG03415.1
INSDC AAG03415.1
NCBI Locus Tag PA0025
protein_id(GenBank) gb|AAG03415.1|AE004442_2|gnl|PseudoCAP|PA0025
TIGR NTL03PA00026
UniParc UPI0000125FF0
UniProtKB Acc P43904
UniProtKB ID AROE_PSEAE
UniRef100 UniRef100_P43904
UniRef50 UniRef50_A1S1K8
UniRef90 UniRef90_P43904

Product

Feature Type CDS
Coding Frame 1
Product Name
shikimate dehydrogenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.39
Kyte-Doolittle Hydrophobicity Value -0.023
Molecular Weight (kDa) 29.5
Isoelectric Point (pI) 5.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 607 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000025 (555 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0025
Search term: aroE

Human Homologs

References

Sequencing and overexpression of the Escherichia coli aroE gene encoding shikimate dehydrogenase.
Anton IA, Coggins JR
Biochem J 1988 Jan 15;249(2):319-26
PubMed ID: 3277621