Pseudomonas aeruginosa UCBPP-PA14, PA14_01020 (hsiC1)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa UCBPP-PA14 - Assembly GCF_000014625.1
GCF_000014625.1|latest |
| Locus Tag |
PA14_01020
|
| Name |
hsiC1
Synonym: tssC1 |
| Replicon | chromosome |
| Genomic location | 99431 - 100927 (+ strand) |
| Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
| Transposon Mutants in orthologs | 8 transposon mutants in orthologs |
| Comment | Hcp Secretion Island-I-encoded type VI secretion system (H1-T6SS) |
Cross-References
| RefSeq | YP_788241.1 |
| GI | 116053804 |
| Entrez | 4383502 |
| INSDC | ABJ15040.1 |
| NCBI Locus Tag | PA14_01020 |
| UniParc | UPI00000C4F25 |
| UniProtKB Acc | Q02UZ5 |
| UniProtKB ID | Q02UZ5_PSEAB |
| UniRef100 | UniRef100_Q9I748 |
| UniRef50 | UniRef50_Q4K3N7 |
| UniRef90 | UniRef90_Q4K3N7 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
HsiC1
|
| Synonyms |
hypothetical protein |
| Evidence for Translation | |
| Charge (pH 7) | -16.24 |
| Kyte-Doolittle Hydrophobicity Value | -0.428 |
| Molecular Weight (kDa) | 55.8 |
| Isoelectric Point (pI) | 4.98 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5N8N | STRUCTURAL PROTEIN | 02/23/17 | Contracted sheath of a Pseudomonas aeruginosa type six secretion system consisting of TssB1 and TssC1 | Pseudomonas aeruginosa | 3.28 | ELECTRON MICROSCOPY | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000083 (1261 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_01020
Search term: hsiC1
Search term: HsiC1
|
Human Homologs
References
|
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999
|
|
Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes.
Förster A, Planamente S, Manoli E, Lossi NS, Freemont PS, Filloux A.
J Biol Chem. 2014 Nov 21;289(47):33032-43.
PubMed ID: 25305017
|