Pseudomonas aeruginosa UCBPP-PA14, PA14_02220

Cytoplasmic Membrane
Outer Membrane
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
Locus Tag
Replicon chromosome
Genomic location 198460 - 200499 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs


RefSeq YP_788334.1
GI 116053897
Entrez 4383576
INSDC ABJ15133.1
NCBI Locus Tag PA14_02220
UniParc UPI000045D3A4
UniProtKB Acc Q02UQ2
UniRef100 UniRef100_S0I327
UniRef50 UniRef50_Q9I6V6
UniRef90 UniRef90_Q9I6V6


Feature Type CDS
Coding Frame 1
Product Name
chemotaxis transducer
Evidence for Translation
Charge (pH 7) -18.01
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 72.6
Isoelectric Point (pI) 4.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4I44 SIGNALING PROTEIN 11/27/12 Aer2 poly-HAMP domains: V33G HAMP1 inverted signaling mutant Pseudomonas aeruginosa 2.88 X-RAY DIFFRACTION 99.4
4HI4 SIGNALING PROTEIN 10/11/12 Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa Pseudomonas aeruginosa 2.304 X-RAY DIFFRACTION 95.0
3VOL SIGNALING PROTEIN 01/27/12 X-ray Crystal Structure of PAS-HAMP Aer2 in the CN-bound Form Pseudomonas aeruginosa 2.399 X-RAY DIFFRACTION 97.2
3LNR SIGNALING PROTEIN 02/02/10 Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2 Pseudomonas aeruginosa 2.64 X-RAY DIFFRACTION 100.0
4I3M SIGNALING PROTEIN 11/26/12 Aer2 poly-HAMP domains: L44H HAMP1 CW-lock mutant Pseudomonas aeruginosa 1.95 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000174 (385 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA14_02220

Human Homologs


No references are associated with this feature.