Pseudomonas aeruginosa UCBPP-PA14, PA14_05740

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_05740
Name
Replicon chromosome
Genomic location 506831 - 508108 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788613.1
GI 116054170
EC Number 1.3.1.1
Entrez 4384307
INSDC ABJ15406.1
NCBI Locus Tag PA14_05740
UniParc UPI0000E448C9
UniProtKB Acc Q02TX3
UniProtKB ID Q02TX3_PSEAB
UniRef100 UniRef100_K1DSJ0
UniRef50 UniRef50_G8QBC2
UniRef90 UniRef90_G8QBC2

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydropyrimidine dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -10.11
Kyte-Doolittle Hydrophobicity Value -0.083
Molecular Weight (kDa) 46.2
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 364 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000430 (922 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_05740

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012]
E-value: 9.5e-60
Percent Identity: 31.4

References

No references are associated with this feature.