Pseudomonas aeruginosa UCBPP-PA14, PA14_18985 (vgrG4b)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_18985
Name
vgrG4b
Replicon chromosome
Genomic location 1638977 - 1641403 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 48 transposon mutants in orthologs

Cross-References

RefSeq YP_789661.1
GI 116054425
Entrez 4384198
INSDC ABJ15661.1
NCBI Locus Tag PA14_18985
UniParc UPI0000E44971
UniProtKB Acc Q02QX5
UniProtKB ID Q02QX5_PSEAB
UniRef100 UniRef100_Q02QX5
UniRef50 UniRef50_Q9HYC3
UniRef90 UniRef90_Q9HYC3

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG4b
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -16.80
Kyte-Doolittle Hydrophobicity Value -0.571
Molecular Weight (kDa) 90587.6
Isoelectric Point (pI) 6.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 151 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_18985
Search term: vgrG4b
Search term: VgrG4b

Human Homologs

References

An rhs gene linked to the second type VI secretion cluster is a feature of the Pseudomonas aeruginosa strain PA14.
Jones C, Hachani A, Manoli E, Filloux A
J Bacteriol 2014 Feb;196(4):800-10
PubMed ID: 24317402
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999