Pseudomonas aeruginosa UCBPP-PA14, PA14_21490 (tle1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_21490
Name
tle1
Replicon chromosome
Genomic location 1863075 - 1865723 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 48 transposon mutants in orthologs

Cross-References

RefSeq YP_789863.1
GI 116051305
Entrez 4381309
INSDC ABJ12541.1
NCBI Locus Tag PA14_21490
UniParc UPI0000E44995
UniProtKB Acc Q02QC3
UniProtKB ID Q02QC3_PSEAB
UniRef100 UniRef100_Q02QC3
UniRef50 UniRef50_Q9HYV3
UniRef90 UniRef90_Q9HYV3

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion lipase effector Tle1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -15.88
Kyte-Doolittle Hydrophobicity Value -0.277
Molecular Weight (kDa) 96.6
Isoelectric Point (pI) 5.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4O5P HYDROLASE 12/19/13 Crystal structure of an uncharacterized protein from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.001 X-RAY DIFFRACTION 98.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 27 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_21490
Search term: tle1

Human Homologs

References

The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting.
Sana TG, Berni B, Bleves S
Front Cell Infect Microbiol 2016;6:61
PubMed ID: 27376031