Pseudomonas aeruginosa UCBPP-PA14, PA14_32410 (mexT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_32410
Name
mexT
Replicon chromosome
Genomic location 2818839 - 2819753 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 13 transposon mutants in orthologs

Cross-References

RefSeq YP_790745.1
GI 116050436
Entrez 4382679
INSDC ABJ11672.1
NCBI Locus Tag PA14_32410
UniParc UPI0000395DCA
UniProtKB Acc Q02MU1
UniProtKB ID Q02MU1_PSEAB
UniRef100 UniRef100_W0YYH0
UniRef50 UniRef50_Q9I0Z0
UniRef90 UniRef90_A6V4X1

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator MexT
Synonyms
Evidence for Translation
Charge (pH 7) 0.70
Kyte-Doolittle Hydrophobicity Value -0.066
Molecular Weight (kDa) 33.4
Isoelectric Point (pI) 7.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexT MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS. [PMID:11040437, PMID:26833155, PMID:10515918] ARO:3000814 protein overexpression model Strict 524.6 99.63 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6L33 TRANSCRIPTION 10/08/19 Crystal structure of the regulatory domain of MexT, a transcriptional activator in Pseudomonas aeruginosa Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 325 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001179 (1943 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_32410
Search term: mexT

Human Homologs

References

No references are associated with this feature.