Pseudomonas aeruginosa UCBPP-PA14, PA14_48115 (aprD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_48115
Name
aprD
Replicon chromosome
Genomic location 4282067 - 4283848 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_791999.1
GI 116054421
Entrez 4384194
INSDC ABJ15657.1
NCBI Locus Tag PA14_48115
UniParc UPI0000E44B46
UniProtKB Acc Q02J87
UniProtKB ID Q02J87_PSEAB
UniRef100 UniRef100_Q02J87
UniRef50 UniRef50_Q03024
UniRef90 UniRef90_Q03024

Product

Feature Type CDS
Coding Frame 1
Product Name
alkaline protease secretion protein AprD
Synonyms
Evidence for Translation
Charge (pH 7) 8.88
Kyte-Doolittle Hydrophobicity Value 0.208
Molecular Weight (kDa) 63.7
Isoelectric Point (pI) 9.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001198 (779 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48115
Search term: aprD

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46]
E-value: 1.1e-34
Percent Identity: 28.8
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46]
E-value: 1.1e-34
Percent Identity: 28.8

References

No references are associated with this feature.