Pseudomonas aeruginosa UCBPP-PA14, PA14_51880 (oprD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_51880
Name
oprD
Replicon chromosome
Genomic location 4606220 - 4607551 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 12 transposon mutants in orthologs

Cross-References

RefSeq YP_792316.1
GI 116048883
Entrez 4380036
INSDC ABJ10119.1
NCBI Locus Tag PA14_51880
UniParc UPI0000E44B7B
UniProtKB Acc Q02IC0
UniProtKB ID Q02IC0_PSEAB
UniRef100 UniRef100_Q02IC0
UniRef50 UniRef50_P32722
UniRef90 UniRef90_P32722

Product

Feature Type CDS
Coding Frame 1
Product Name
basic amino acid, basic peptide and imipenem outer membrane porin OprD precursor
Synonyms
Evidence for Translation
Charge (pH 7) -14.55
Kyte-Doolittle Hydrophobicity Value -0.463
Molecular Weight (kDa) 48.2
Isoelectric Point (pI) 4.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2ODJ MEMBRANE PROTEIN 12/22/06 Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.9 X-RAY DIFFRACTION 97.8
4FOZ PROTEIN TRANSPORT 06/21/12 Crystal Structure of OccD1 (OprD) Y282R/D307H PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 97.1
3SY7 MEMBRANE PROTEIN 07/15/11 Improved crystal structure of Pseudomonas aeruginosa OprD PSEUDOMONAS AERUGINOSA 2.15 X-RAY DIFFRACTION 97.6

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
(Hydroxyethyloxy)Tri(Ethyloxy)Octane DB04233 DrugBank 5.1.4 P32722 Porin D 98.0 443 1.8e-253

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 16 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000187 (1618 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51880
Search term: oprD

References

No references are associated with this feature.