Pseudomonas aeruginosa UCBPP-PA14, PA14_72490 (polA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_72490
Name
polA
Replicon chromosome
Genomic location 6456695 - 6459436 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_793970.1
GI 116053643
Entrez 4385162
INSDC ABJ14879.1
NCBI Locus Tag PA14_72490
UniParc UPI000045D33B
UniProtKB Acc Q02DL6
UniProtKB ID Q02DL6_PSEAB
UniRef100 UniRef100_Q02DL6
UniRef50 UniRef50_Q9HT80
UniRef90 UniRef90_Q9HT80

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase I
Synonyms
Evidence for Translation
Charge (pH 7) -30.11
Kyte-Doolittle Hydrophobicity Value -0.139
Molecular Weight (kDa) 99.8
Isoelectric Point (pI) 4.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 592 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005032 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_72490
Search term: polA
Search term: DNA polymerase I

Human Homologs

Ensembl 110, assembly GRCh38.p14
DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870]
E-value: 3.7e-53
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870]
E-value: 3.7e-53
Percent Identity: 30.5

References

No references are associated with this feature.