Pseudomonas aeruginosa RP73, M062_00470

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_00470
Name
Replicon chromosome
Genomic location 112001 - 113941 (+ strand)

Cross-References

RefSeq YP_008130560.1
GI 514407719
Entrez 15957837
NCBI Locus Tag M062_00470

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion protein ImpA
Synonyms
Evidence for Translation
Charge (pH 7) -7.09
Kyte-Doolittle Hydrophobicity Value -0.528
Molecular Weight (kDa) 72.3
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4MTK TOXIN 09/19/13 Crystal structure of PA0091 VgrG1, the central spike of the Type VI Secretion System Pseudomonas aeruginosa 3.322 X-RAY DIFFRACTION 99.7
4UHV STRUCTURAL PROTEIN 03/25/15 The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 99.7
6H3L TOXIN 07/19/18 Structure of VgrG1 in the Type VI secretion pre-firing VgrG1-Tse6-EagT6-EF-Tu-Tsi6 complex Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 4.2 ELECTRON MICROSCOPY 99.7
6H3N TOXIN 07/19/18 Structure of VgrG1 in the Type VI secretion VgrG1-Tse6-EF-Tu complex embedded in lipid nanodiscs Pseudomonas aeruginosa PAO1 3.25 ELECTRON MICROSCOPY 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 155 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_00470

Human Homologs

References

No references are associated with this feature.