Pseudomonas denitrificans ATCC 13867, H681_17825 (aspS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in GBrowse

Gene Feature Overview

Strain Pseudomonas denitrificans ATCC 13867
GCF_000349845.1|latest
Locus Tag
H681_17825
Name
aspS
Replicon chromosome
Genomic location 4014304 - 4016079 (- strand)

Cross-References

RefSeq YP_007658972.1
GI 472326726
EC Number 6.1.1.12
Entrez 14997690
INSDC AGI25432.1
NCBI Locus Tag H681_17825
UniParc UPI0002C4E7C0
UniProtKB Acc M4X323
UniProtKB ID M4X323_PSEDE
UniRef100 UniRef100_M4X323
UniRef50 UniRef50_Q83BE5
UniRef90 UniRef90_C1DRG2

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartyl-tRNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) -13.22
Kyte-Doolittle Hydrophobicity Value -0.331
Molecular Weight (kDa) 66362.1
Isoelectric Point (pI) 5.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WJ3 LIGASE/RNA 09/29/14 Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA PAO1; SYNTHETIC CONSTRUCT 3.705 X-RAY DIFFRACTION 94.9
4WJ4 LIGASE/RNA 09/29/14 Crystal structure of non-discriminating aspartyl-tRNA synthetase from Pseudomonas aeruginosa complexed with tRNA(Asn) and aspartic acid PSEUDOMONAS AERUGINOSA PAO1; SYNTHETIC CONSTRUCT 3.294 X-RAY DIFFRACTION 94.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000928 (554 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H681_17825
Search term: aspS

Human Homologs

Ensembl 97, assembly GRCh38.p12
aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]
E-value: 8.0e-114
Percent Identity: 39.1

References

No references are associated with this feature.