Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5498
|
Name |
znuA
Synonym: znuA |
Replicon | chromosome |
Genomic location | 6191186 - 6192109 (- strand) |
Transposon Mutants | 7 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Structural similarity to 2XQV (zinc transporter ZnuA from Salmonella enterica, root-mean-square deviation: 1.7 angstroms). Sequence similarity to 4BBP (98%/39,72%) (ZN). Final predicted ligand: zinc Ion (PMID: 31631799) |
RefSeq | NP_254185.1 |
GI | 15600691 |
Affymetrix | PA5498_at |
Entrez | 878912 |
GenBank | AAG08883.1 |
INSDC | AAG08883.1 |
NCBI Locus Tag | PA5498 |
protein_id(GenBank) | gb|AAG08883.1|AE004962_7|gnl|PseudoCAP|PA5498 |
TIGR | NTL03PA05499 |
UniParc | UPI00000C6039 |
UniProtKB Acc | Q9HT75 |
UniProtKB ID | Q9HT75_PSEAE |
UniRef100 | UniRef100_Q9HT75 |
UniRef50 | UniRef50_I7C2G8 |
UniRef90 | UniRef90_Q9HT75 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
ZnuA
|
Synonyms |
probable adhesin |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -5.44 |
Kyte-Doolittle Hydrophobicity Value | -0.086 |
Molecular Weight (kDa) | 33.6 |
Isoelectric Point (pI) | 6.13 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 467 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG005037 (538 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5498
Search term: znuA
Search term: ZnuA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
The transcriptional regulator Np20 is the zinc uptake regulator in Pseudomonas aeruginosa.
Ellison ML, Farrow JM 3rd, Parrish W, Danell AS, Pesci EC
PLoS One 2013;8(9):e75389
PubMed ID: 24086521
|
ZnuA and zinc homeostasis in Pseudomonas aeruginosa.
Pederick VG, Eijkelkamp BA, Begg SL, Ween MP, McAllister LJ, Paton JC, McDevitt CA
Sci Rep 2015 Aug 20;5:13139
PubMed ID: 26290475
|
Uncovering the structure and function of Pseudomonas aeruginosa periplasmic proteins by an in silico approach.
Caprari S, Brandi V, Pasquadibisceglie A, Polticelli F
J Biomol Struct Dyn 2020 Sep;38(15):4508-4520
PubMed ID: 31631799
|