Pseudomonas aeruginosa UCBPP-PA14, PA14_13500

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_13500
Name
Replicon	chromosome
Genomic location	1160401 - 1161378 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	3 transposon mutants in orthologs

Cross-References

RefSeq	YP_789224.1
GI	116051933
Entrez	4381941
INSDC	ABJ13169.1
NCBI Locus Tag	PA14_13500
UniParc	UPI0000396203
UniProtKB Acc	Q02S62
UniProtKB ID	Q02S62_PSEAB
UniRef100	UniRef100_W1MHM6
UniRef50	UniRef50_G8QCF7
UniRef90	UniRef90_S0IQW3

Product

Feature Type	CDS
Coding Frame	1
Product Name	2-hydroxyacid dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	4.42
Kyte-Doolittle Hydrophobicity Value	-0.134
Molecular Weight (kDa)	35.7
Isoelectric Point (pI)	9.33

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001776 (524 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_13500 Search term: 2-hydroxyacid dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000313432 glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570] E-value: 2.5e-44 Percent Identity: 39.9

References