Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_13660
|
Name |
tpbA
|
Replicon | chromosome |
Genomic location | 1174167 - 1174823 (- strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | YP_789236.1 |
GI | 116051921 |
Entrez | 4381929 |
INSDC | ABJ13157.1 |
NCBI Locus Tag | PA14_13660 |
UniParc | UPI00003961FB |
UniProtKB Acc | Q02S50 |
UniProtKB ID | Q02S50_PSEAB |
UniRef100 | UniRef100_Q02S50 |
UniRef50 | UniRef50_Q9HXC7 |
UniRef90 | UniRef90_Q9HXC7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
protein tyrosine phosphatase TpbA
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | 1.34 |
Kyte-Doolittle Hydrophobicity Value | -0.121 |
Molecular Weight (kDa) | 24.0 |
Isoelectric Point (pI) | 7.60 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4R0T | HYDROLASE | 08/01/14 | Crystal structure of P. aeruginosa TpbA (C132S) in complex with pTyr | Pseudomonas aeruginosa PAO1 | 2.603 | X-RAY DIFFRACTION | 97.7 |
4R0S | HYDROLASE | 08/01/14 | Crystal structure of P. aeruginosa TpbA | Pseudomonas aeruginosa PAO1 | 2.03 | X-RAY DIFFRACTION | 98.2 |
2M3V | HYDROLASE | 01/26/13 | Solution structure of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonas aeruginosa | Pseudomonas aeruginosa | NOT | SOLUTION NMR | 99.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 32 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001786 (406 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_13660
Search term: tpbA
Search term: protein tyrosine phosphatase TpbA
|
Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885).
Ueda A, Wood TK
PLoS Pathog 2009 Jun;5(6):e1000483
PubMed ID: 19543378
|