Pseudomonas aeruginosa UCBPP-PA14, PA14_64200 (purH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_64200
Name
purH
Replicon chromosome
Genomic location 5719711 - 5721318 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_793320.1
GI 116053002
EC Number 2.1.2.3
EC Number 3.5.4.10
Entrez 4383323
INSDC ABJ14238.1
NCBI Locus Tag PA14_64200
UniParc UPI0000396EDB
UniProtKB Acc Q02FG6
UniProtKB ID PUR9_PSEAB
UniRef100 UniRef100_Q02FG6
UniRef50 UniRef50_B7LAV3
UniRef90 UniRef90_A6VCW0

Product

Feature Type CDS
Coding Frame 1
Product Name
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Synonyms
Evidence for Translation
Charge (pH 7) -3.48
Kyte-Doolittle Hydrophobicity Value -0.058
Molecular Weight (kDa) 57.7
Isoelectric Point (pI) 6.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004483 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_64200
Search term: purH

Human Homologs

Ensembl 110, assembly GRCh38.p14
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:794]
E-value: 2.9e-74
Percent Identity: 34.3

References

No references are associated with this feature.