Pseudomonas aeruginosa UCBPP-PA14, PA14_65230 (purA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_65230
Name	purA
Replicon	chromosome
Genomic location	5813463 - 5814755 (- strand)

Cross-References

RefSeq	YP_793406.1
GI	116053087
EC Number	6.3.4.4
Entrez	4384841
INSDC	ABJ14323.1
NCBI Locus Tag	PA14_65230
UniParc	UPI0000132B01
UniProtKB Acc	Q02F80
UniProtKB ID	PURA_PSEAB
UniRef100	UniRef100_B7V201
UniRef50	UniRef50_Q9KNX8
UniRef90	UniRef90_Q4KJ68

Product

Feature Type	CDS
Coding Frame	1
Product Name	adenylosuccinate synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-7.25
Kyte-Doolittle Hydrophobicity Value	-0.146
Molecular Weight (kDa)	46.8
Isoelectric Point (pI)	5.95

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 640 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004553 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_65230 Search term: purA Search term: adenylosuccinate synthetase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000518203 adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093] E-value: 5.6e-92 Percent Identity: 43.9
Ensembl 110, assembly GRCh38.p14	ENSP00000331260 adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093] E-value: 5.6e-92 Percent Identity: 43.9

References