Pseudomonas aeruginosa PAO1, PA2795 (dusA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2795
Name
dusA
Synonym: yjbN
Synonym: DusA
Replicon chromosome
Genomic location 3152504 - 3153502 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251485.1
GI 15597991
Affymetrix PA2795_at
DNASU PaCD00007213
Entrez 882754
GenBank AAG06183.1
INSDC AAG06183.1
NCBI Locus Tag PA2795
protein_id(GenBank) gb|AAG06183.1|AE004707_2|gnl|PseudoCAP|PA2795
TIGR NTL03PA02795
UniParc UPI00000C580E
UniProtKB Acc Q9I048
UniProtKB ID DUSA_PSEAE
UniRef100 UniRef100_Q9I048
UniRef50 UniRef50_Q9I048
UniRef90 UniRef90_Q9I048

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrouridine synthase A
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.34
Kyte-Doolittle Hydrophobicity Value -0.168
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 7.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 549 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002774 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2795
Search term: dusA

Human Homologs

References

Structural studies on dihydrouridine synthase A (DusA) from Pseudomonas aeruginosa.
Goyal N, Chandra A, Qamar I, Singh N
Int J Biol Macromol 2019 Jul 1;132:254-264
PubMed ID: 30928375