Pseudomonas aeruginosa PAO1, PA2825 (ospR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2825
Name
ospR
Replicon chromosome
Genomic location 3179469 - 3179960 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251515.1
GI 15598021
Affymetrix PA2825_at
DNASU PaCD00007226
Entrez 878886
GenBank AAG06213.1
INSDC AAG06213.1
NCBI Locus Tag PA2825
protein_id(GenBank) gb|AAG06213.1|AE004709_6|gnl|PseudoCAP|PA2825
TIGR NTL03PA02825
UniParc UPI00000C582B
UniProtKB Acc Q9I018
UniProtKB ID Q9I018_PSEAE
UniRef100 UniRef100_W0YTX9
UniRef50 UniRef50_G8Q2V8
UniRef90 UniRef90_A6V3R5

Product

Feature Type CDS
Coding Frame 1
Product Name
OspR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.89
Kyte-Doolittle Hydrophobicity Value -0.081
Molecular Weight (kDa) 18.5
Isoelectric Point (pI) 9.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 262 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002742 (397 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2825
Search term: ospR
Search term: OspR

Human Homologs

References

Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
Lan L, Murray TS, Kazmierczak BI, He C
Mol Microbiol 2010 Jan;75(1):76-91
PubMed ID: 19943895