Pseudomonas aeruginosa PAO1, PA3236 (betX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3236
Name
betX
Replicon chromosome
Genomic location 3623686 - 3624543 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Commentbinds betaine

Cross-References

RefSeq NP_251926.1
GI 15598432
Affymetrix PA3236_at
Entrez 882397
GenBank AAG06624.1
INSDC AAG06624.1
NCBI Locus Tag PA3236
protein_id(GenBank) gb|AAG06624.1|AE004746_8|gnl|PseudoCAP|PA3236
TIGR NTL03PA03236
UniParc UPI00000C5968
UniProtKB Acc Q9HZ04
UniProtKB ID Q9HZ04_PSEAE
UniRef100 UniRef100_W0YVK4
UniRef50 UniRef50_Q3JGN5
UniRef90 UniRef90_A6V2I5

Product

Feature Type CDS
Coding Frame 1
Product Name
BetX
Product Name Confidence: Class 1
Synonyms betaine-specific binding protein
Evidence for Translation
Charge (pH 7) 2.93
Kyte-Doolittle Hydrophobicity Value -0.063
Molecular Weight (kDa) 31.1
Isoelectric Point (pI) 8.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 152 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002378 (513 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3236
Search term: betX
Search term: BetX

Human Homologs

References

OpuA, an osmotically regulated binding protein-dependent transport system for the osmoprotectant glycine betaine in Bacillus subtilis.
Kempf B, Bremer E
J Biol Chem 1995 Jul 14;270(28):16701-13
PubMed ID: 7622480
The ATP-binding cassette transporter Cbc (choline/betaine/carnitine) recruits multiple substrate-binding proteins with strong specificity for distinct quaternary ammonium compounds.
Chen C, Malek AA, Wargo MJ, Hogan DA, Beattie GA
Mol Microbiol 2010 Jan;75(1):29-45
PubMed ID: 19919675