Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3792
|
Name |
leuA
|
Replicon | chromosome |
Genomic location | 4250828 - 4252606 (+ strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_252481.3 |
GI | 161486762 |
Affymetrix | PA3792_leuA_at |
Entrez | 879941 |
GenBank | AAG07179.1 |
INSDC | AAG07179.1 |
NCBI Locus Tag | PA3792 |
protein_id(GenBank) | gb|AAG07179.1|AE004798_2|gnl|PseudoCAP|PA3792 |
TIGR | NTL03PA03792 |
UniParc | UPI000012E4CC |
UniProtKB Acc | Q9HXK5 |
UniProtKB ID | LEU1_PSEAE |
UniRef100 | UniRef100_Q9HXK5 |
UniRef50 | UniRef50_Q9HXK5 |
UniRef90 | UniRef90_Q9HXK5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
2-isopropylmalate synthase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -13.27 |
Kyte-Doolittle Hydrophobicity Value | -0.271 |
Molecular Weight (kDa) | 65.8 |
Isoelectric Point (pI) | 5.50 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 573 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001874 (534 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3792
Search term: leuA
Search term: 2-isopropylmalate synthase
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis.
Pátek M, Krumbach K, Eggeling L, Sahm H
Appl Environ Microbiol 1994 Jan;60(1):133-40
PubMed ID: 8117072
|