Pseudomonas aeruginosa PAO1, PA3838

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3838
Name
Replicon chromosome
Genomic location 4299204 - 4299998 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252527.1
GI 15599033
Affymetrix PA3838_at
DNASU PaCD00007673
Entrez 879859
GenBank AAG07225.1
INSDC AAG07225.1
NCBI Locus Tag PA3838
protein_id(GenBank) gb|AAG07225.1|AE004801_3|gnl|PseudoCAP|PA3838
TIGR NTL03PA03838
UniParc UPI00000C5B35
UniProtKB Acc Q9HXG6
UniProtKB ID Q9HXG6_PSEAE
UniRef100 UniRef100_W0YUI2
UniRef50 UniRef50_A0A083ZW64
UniRef90 UniRef90_A6V0S5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Detected using LC-MS/MS (28.44 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.06
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 28.4
Isoelectric Point (pI) 6.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001828 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3838

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33]
E-value: 1.1e-13
Percent Identity: 27.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33]
E-value: 1.1e-13
Percent Identity: 27.3

References

Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344