Pseudomonas aeruginosa PAO1, PA3870 (moaA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3870
Name
moaA1
Replicon chromosome
Genomic location 4333357 - 4334346 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252559.1
GI 15599065
Affymetrix PA3870_moaA1_at
DNASU PaCD00007686
Entrez 879786
GenBank AAG07257.1
INSDC CAA75545.1
NCBI Locus Tag PA3870
protein_id(GenBank) gb|AAG07257.1|AE004804_5|gnl|PseudoCAP|PA3870
TIGR NTL03PA03870
UniParc UPI000012F2CD
UniProtKB Acc Q9HXD6
UniProtKB ID MOAA1_PSEAE
UniRef100 UniRef100_Q9HXD6
UniRef50 UniRef50_Q9HXD6
UniRef90 UniRef90_Q9HXD6

Product

Feature Type CDS
Coding Frame 1
Product Name
molybdopterin biosynthetic protein A1
Product Name Confidence: Class 2
Synonyms molybdenum cofactor biosynthetic protein A
Evidence for Translation
Charge (pH 7) 5.90
Kyte-Doolittle Hydrophobicity Value -0.119
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 8.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 553 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001801 (851 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3870
Search term: moaA1

Human Homologs

Ensembl 110, assembly GRCh38.p14
molybdenum cofactor synthesis 1 [Source:HGNC Symbol;Acc:HGNC:7190]
E-value: 2.3e-53
Percent Identity: 41.1
Ensembl 110, assembly GRCh38.p14
molybdenum cofactor synthesis 1 [Source:HGNC Symbol;Acc:HGNC:7190]
E-value: 2.3e-53
Percent Identity: 41.1

References

A pAO1-encoded molybdopterin cofactor gene (moaA) of Arthrobacter nicotinovorans: characterization and site-directed mutagenesis of the encoded protein.
Menéndez C, Igloi G, Henninger H, Brandsch R
Arch Microbiol 1995 Aug;164(2):142-51
PubMed ID: 8588735