Pseudomonas aeruginosa PAO1, PA3925

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3925
Name
Replicon chromosome
Genomic location 4400123 - 4401298 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252614.1
GI 15599120
Affymetrix PA3925_at
DNASU PaCD00007711
Entrez 879047
GenBank AAG07312.1
INSDC AAG07312.1
NCBI Locus Tag PA3925
protein_id(GenBank) gb|AAG07312.1|AE004810_4|gnl|PseudoCAP|PA3925
TIGR NTL03PA03925
UniParc UPI00000D425C
UniProtKB Acc G3XD40
UniProtKB ID G3XD40_PSEAE
UniRef100 UniRef100_X6ZBU1
UniRef50 UniRef50_D7HZ68
UniRef90 UniRef90_A0A024HLQ4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyl-CoA thiolase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.46
Kyte-Doolittle Hydrophobicity Value 0.078
Molecular Weight (kDa) 40.6
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001749 (322 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3925

Human Homologs

Ensembl 110, assembly GRCh38.p14
acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93]
E-value: 8.9e-89
Percent Identity: 46.3

References

No references are associated with this feature.