Pseudomonas aeruginosa PAO1, PA3929 (cioB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3929
Name
cioB
Replicon chromosome
Genomic location 4403891 - 4404898 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252618.1
GI 15599124
Affymetrix PA3929_cioB_at
DNASU PaCD00007714
Entrez 879044
GenBank AAG07316.1
INSDC AAG07316.1
NCBI Locus Tag PA3929
protein_id(GenBank) gb|AAG07316.1|AE004810_8|gnl|PseudoCAP|PA3929
TIGR NTL03PA03929
UniParc UPI00000D4238
UniProtKB Acc G3XD05
UniProtKB ID G3XD05_PSEAE
UniRef100 UniRef100_W0YZ02
UniRef50 UniRef50_R4YCU1
UniRef90 UniRef90_W0YZ02

Product

Feature Type CDS
Coding Frame 1
Product Name
cyanide insensitive terminal oxidase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.37
Kyte-Doolittle Hydrophobicity Value 0.863
Molecular Weight (kDa) 37.0
Isoelectric Point (pI) 7.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 400 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001746 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3929
Search term: cioB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The cioAB genes from Pseudomonas aeruginosa code for a novel cyanide-insensitive terminal oxidase related to the cytochrome bd quinol oxidases.
Cunningham L, Pitt M, Williams HD
Mol Microbiol 1997 May;24(3):579-91
PubMed ID: 9179851