Pseudomonas aeruginosa PAO1, PA3954 (sfnG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3954
Name
sfnG
Replicon chromosome
Genomic location 4434150 - 4435244 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_252643.1
GI 15599149
Affymetrix PA3954_at
Entrez 878845
GenBank AAG07341.1
INSDC AAG07341.1
NCBI Locus Tag PA3954
protein_id(GenBank) gb|AAG07341.1|AE004813_8|gnl|PseudoCAP|PA3954
TIGR NTL03PA03954
UniParc UPI00000C5B96
UniProtKB Acc Q9HX62
UniProtKB ID Q9HX62_PSEAE
UniRef100 UniRef100_W0YZ28
UniRef50 UniRef50_Q4KBL5
UniRef90 UniRef90_A0A031E3Y6

Product

Feature Type CDS
Coding Frame 1
Product Name
FMNH2-dependent monooxygenase, SfnG
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.58
Kyte-Doolittle Hydrophobicity Value -0.331
Molecular Weight (kDa) 40.7
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 256 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001724 (1790 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3954
Search term: sfnG

Human Homologs

References

The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate.
Wicht DK
Arch Biochem Biophys 2016 Aug 15;604:159-66
PubMed ID: 27392454