Pseudomonas aeruginosa PAO1, PA4960

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4960
Name
Synonym: serB
Replicon chromosome
Genomic location 5567655 - 5568944 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253647.1
GI 15600153
Affymetrix PA4960_at
Entrez 878558
GenBank AAG08345.1
INSDC AAG08345.1
NCBI Locus Tag PA4960
protein_id(GenBank) gb|AAG08345.1|AE004909_1|gnl|PseudoCAP|PA4960
TIGR NTL03PA04961
UniParc UPI00000C5E97
UniProtKB Acc Q9HUK5
UniProtKB ID Q9HUK5_PSEAE
UniRef100 UniRef100_Q02F58
UniRef50 UniRef50_Q4KJ88
UniRef90 UniRef90_Q4KJ88

Product

Feature Type CDS
Coding Frame 1
Product Name
probable phosphoserine phosphatase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.31
Kyte-Doolittle Hydrophobicity Value 0.026
Molecular Weight (kDa) 46.4
Isoelectric Point (pI) 4.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004575 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4960

Human Homologs

Ensembl 110, assembly GRCh38.p14
phosphoserine phosphatase [Source:HGNC Symbol;Acc:HGNC:9577]
E-value: 3.4e-17
Percent Identity: 34.8
Ensembl 110, assembly GRCh38.p14
phosphoserine phosphatase [Source:HGNC Symbol;Acc:HGNC:9577]
E-value: 3.4e-17
Percent Identity: 34.8
Ensembl 110, assembly GRCh38.p14
phosphoserine phosphatase [Source:HGNC Symbol;Acc:HGNC:9577]
E-value: 3.4e-17
Percent Identity: 34.8

References

Construction and analysis of plasmids containing the Escherichia coli serB gene.
Garnant MK, Stauffer GV
Mol Gen Genet 1984;193(1):72-5
PubMed ID: 6318053
DNA sequence and characterization of the Escherichia coli serB gene.
Neuwald AF, Stauffer GV
Nucleic Acids Res 1985 Oct 11;13(19):7025-39
PubMed ID: 2997734
Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.
Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR
Nucleic Acids Res 1995 Jun 25;23(12):2105-19
PubMed ID: 7610040