Pseudomonas aeruginosa PAO1, PA0119

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0119
Name
Replicon chromosome
Genomic location 138818 - 140167 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248809.1
GI 15595317
Affymetrix PA0119_at
Entrez 877578
GenBank AAG03509.1
NCBI Locus Tag PA0119
protein_id(GenBank) gb|AAG03509.1|AE004450_4|gnl|PseudoCAP|PA0119
TIGR NTL03PA00120
UniProtKB Acc Q9I713
UniProtKB ID DCTA1_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable dicarboxylate transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 4.77
Kyte-Doolittle Hydrophobicity Value 0.907
Molecular Weight (kDa) 47.4
Isoelectric Point (pI) 8.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000117 (441 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0119

Human Homologs

References

Analysis of the C4-dicarboxylate transport genes of Rhizobium meliloti: nucleotide sequence and deduced products of dctA, dctB, and dctD.
Watson RJ
Mol Plant Microbe Interact 1990 May-Jun;3(3):174-81
PubMed ID: 2134335
The membrane topology of the Rhizobium meliloti C4-dicarboxylate permease (DctA) as derived from protein fusions with Escherichia coli K12 alkaline phosphatase (PhoA) and beta-galactosidase (LacZ).
Jording D, Pühler A
Mol Gen Genet 1993 Oct;241(1-2):106-14
PubMed ID: 8232193