Pseudomonas aeruginosa PAO1, PA0155 (pcaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0155
Name
pcaR
Replicon chromosome
Genomic location 176315 - 177154 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248845.1
GI 15595353
Affymetrix PA0155_pcaR_at
DNASU PaCD00006067
Entrez 882136
GenBank AAG03545.1
INSDC AAG03545.1
NCBI Locus Tag PA0155
protein_id(GenBank) gb|AAG03545.1|AE004453_8|gnl|PseudoCAP|PA0155
TIGR NTL03PA00156
UniParc UPI00000C4F6A
UniProtKB Acc Q9I6X7
UniProtKB ID Q9I6X7_PSEAE
UniRef100 UniRef100_W0YK42
UniRef50 UniRef50_Q52154
UniRef90 UniRef90_A6UXU4

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator PcaR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.25
Kyte-Doolittle Hydrophobicity Value 0.051
Molecular Weight (kDa) 30.6
Isoelectric Point (pI) 7.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 330 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000153 (631 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0155
Search term: pcaR

Human Homologs

References

Characterization of the pcaR regulatory gene from Pseudomonas putida, which is required for the complete degradation of p-hydroxybenzoate.
Romero-Steiner S, Parales RE, Harwood CS, Houghton JE
J. Bacteriol. 1994 Sep;176(18):5771-9
PubMed ID: 8083169