Pseudomonas aeruginosa PAO1, PA0228 (pcaF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0228
|
| Name |
pcaF
|
| Replicon | chromosome |
| Genomic location | 257108 - 258313 (+ strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248919.1 |
| GI | 15595425 |
| Affymetrix | PA0228_pcaF_at |
| Entrez | 877715 |
| GenBank | AAG03617.1 |
| INSDC | AAG03617.1 |
| NCBI Locus Tag | PA0228 |
| protein_id(GenBank) | gb|AAG03617.1|AE004460_10|gnl|PseudoCAP|PA0228 |
| TIGR | NTL03PA00229 |
| UniParc | UPI00000C4FAB |
| UniProtKB Acc | Q9I6R0 |
| UniProtKB ID | PCAF_PSEAE |
| UniRef100 | UniRef100_Q9I6R0 |
| UniRef50 | UniRef50_P0C7L2 |
| UniRef90 | UniRef90_Q9I6R0 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
beta-ketoadipyl CoA thiolase PcaF
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.96 |
| Kyte-Doolittle Hydrophobicity Value | 0.007 |
| Molecular Weight (kDa) | 42.1 |
| Isoelectric Point (pI) | 5.52 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000227 (544 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0228
Search term: pcaF
Search term: beta-ketoadipyl CoA thiolase PcaF
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]
E-value:
1.3e-79
Percent Identity:
42.4
|
References
|
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J. Bacteriol. 1994 Nov;176(21):6479-88
PubMed ID: 7961399
|