Pseudomonas aeruginosa PAO1, PA1049 (pdxH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1049
Name
pdxH
Replicon chromosome
Genomic location 1136388 - 1137035 (+ strand)

Cross-References

RefSeq NP_249740.1
GI 15596246
Affymetrix PA1049_pdxH_at
DNASU PaCD00006482
Entrez 881467
GenBank AAG04438.1
INSDC AAG04438.1
NCBI Locus Tag PA1049
protein_id(GenBank) gb|AAG04438.1|AE004537_3|gnl|PseudoCAP|PA1049
TIGR NTL03PA01050
UniParc UPI00000C5223
UniProtKB Acc Q9I4S5
UniProtKB ID PDXH_PSEAE
UniRef100 UniRef100_Q9I4S5
UniRef50 UniRef50_Q9KKM4
UniRef90 UniRef90_Q9I4S5

Product

Feature Type CDS
Coding Frame 1
Product Name
pyridoxine 5'-phosphate oxidase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.34
Kyte-Doolittle Hydrophobicity Value -0.726
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 6.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 351 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001011 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1049
Search term: pdxH

Human Homologs

References

Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations.
Lam HM, Winkler ME
J Bacteriol 1992 Oct;174(19):6033-45
PubMed ID: 1356963
Kinetic limitation and cellular amount of pyridoxine (pyridoxamine) 5'-phosphate oxidase of Escherichia coli K-12.
Zhao G, Winkler ME
J. Bacteriol. 1995 Feb;177(4):883-91
PubMed ID: 7860596