Pseudomonas aeruginosa PAO1, PA1501

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1501
Name
Synonym: gip
Replicon chromosome
Genomic location 1630024 - 1630806 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_250192.1
GI 15596698
Affymetrix PA1501_at
DNASU PaCD00006688
Entrez 879362
GenBank AAG04890.1
INSDC AAG04890.1
NCBI Locus Tag PA1501
protein_id(GenBank) gb|AAG04890.1|AE004579_2|gnl|PseudoCAP|PA1501
TIGR NTL03PA01502
UniParc UPI00000C53AF
UniProtKB Acc Q9I3L1
UniProtKB ID Q9I3L1_PSEAE
UniRef100 UniRef100_Q9I3L1
UniRef50 UniRef50_Q4KG07
UniRef90 UniRef90_A6V7Z9

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms glyoxylate-induced protein
Evidence for Translation
Charge (pH 7) -8.47
Kyte-Doolittle Hydrophobicity Value -0.225
Molecular Weight (kDa) 29.2
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000534 (866 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1501

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxypyruvate isomerase (putative) [Source:HGNC Symbol;Acc:HGNC:26948]
E-value: 4.4e-52
Percent Identity: 42.4

References

Molecular cloning, DNA sequencing, and biochemical analyses of Escherichia coli glyoxylate carboligase. An enzyme of the acetohydroxy acid synthase-pyruvate oxidase family.
Chang YY, Wang AY, Cronan JE Jr
J Biol Chem 1993 Feb 25;268(6):3911-9
PubMed ID: 8440684